Onychomycosis commercial products include Griseoflulvin, Itraconazole, Terbinafine and Ciclopirox 8% nail lacquer,
known as (Penlac). Griseofulvin has reported poor cure rates and requires 10 to 18 months of use. Oral therapy with Itra conazole and Terbinafine also present problems with drug interactions and a very high potential
for liver toxicity. A patient with compromised liver function or a GERD patient on a PPI will not
be a candidate for oral Itraconazole. Having a specially formulated compounded product may
overcome these problems and avoid the need for extensive liver monitoring; results may also
occur faster. Nail fungus can be painful and cause permanent damage to nails. It may lead to
other serious infections if the immune system is suppressed due to medications, diabetes,
and other conditions.
We can dissolve an antifungal in dimethylsulfoxide or DMSO that has superior nail penetration
and is able to deliver an antifungal to the site of infection. This formulation comes in a nail polish that is easily applied.